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Tips for hvordan finne resultater fra medisinske DC prosjekter
shauge
#1 Posted : Saturday, April 02, 2011 10:33:05 AM(UTC)
shauge

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Thanks: 4 times
Georgios driver EMBnet (European Molecual Biologists) noden i Norge. Dette nettverket inneholder my informasjon som kommer fra mange forskere. Jeg spurte derfor Georgios om det kom noe informasjon fra noen av de mange DC-prosjektene som driver med medisinsk forskning. Jeg sa at jeg savnet at de offentliggjør "papers" som beskriver fremskritt de gjør i forskningen sin. Hans svar var at de offentliggjør resultater og han hadde noen tips for å søke etter resultater. Jeg synest fortsatt at det ikke er lett å finne resultater fra et spesifikt prosjekt, men likevel dette er sikkert nyttige tips hvis noen ønsker å søke etter resultater. Jeg gjengir hans tips her:
Quote:
The first (and perhaps the most important one) is the fact that D2OL and other DC paradigms do not offer something extremely novel to write a paper about. Don't get me wrong, I am not saying that there is nothing to DC, but it is a utility, an infrastructure issue. As such, when a DC based project publishes something, it will (normally) be in a computing journal, normally under the Distributed, Parallel, Cluster and lately Grid computation areas. IEEE Xplore and ACM procedings are good examples (google them), where a composite search with the aformentioned keywords will give you hits. The algorithm that the DC utility runs is another story and this is where the important publishing results (as far as the life science is concerned) are located. D2OL for instance, goes by the keyword of 'ligand docking', a general field of protein docking and molecular modeling, with links to structural bioinformatics, the subfield of bioinformatics that has to do with protein function. Good examples of journals where you can search for the latest advances in the field are: http://bioinformatics.oxfordjournals.org/ and use keyword searches such as 'ligand docking'. This is the stuff that makes publications and allows scientists to target ligands to proteins in silico, identify candidates and then replicate only the promising results in the labs to make drugs such as tamiflu and others. Consequently, when a scientist publishes something in the life science field, the effort goes into explaining the algorithm in detail, rather than the infrastructure. In the same way, most papers about climate modeling focus on the model itself, rather than the computing paradigm. The whole idea about a DC based grid is afterall to act as a utility, a platform to run your algorithm on and get your results.
brage
#2 Posted : Saturday, April 02, 2011 10:33:05 AM(UTC)
brage

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Virkelig et godt initiativ dette [:)] Det skal bli interessant å se utviklingen i fremtiden. Jeg må stadig minne meg selv om at medisinsk forskning ved hjelp av datakraft er nokså nytt og at man derfor kanskje ikke skal forvente de helt store gjennombruddene enda. Men på den annen side er det jo helt klart forskjell på de forskjellige prosjektene. Noen fremstår som mer troverdige enn andre i mine øyne. Det ser ut som et veldig interessant nettsted han linker til. Jeg ser at Vijay Pande er blant referansene i flere av artiklene i Oxford Journals, blant annet denne . Takker så meget
Junta
#3 Posted : Saturday, April 02, 2011 10:33:05 AM(UTC)
Junta

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Takk for info. shauge og Georgios. Denne burde vært på forsiden, for dette bør alle få med seg. [:)]
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